drug相关论文
30. Knockdown of IGF-IR by Antisense Oligodeoxynucleotide auguments the sensitivity of bladder cance
AND AIM: Transitional cell carcinoma (TCC) of the bladder represents the fifth most prevalent malignancy in Western popu......
Since the early 2000s, the popularity of zebrafish in in vivo drug screening has shown a substantial increase. The zebra......
In recent decades,the development of high-performance computing (HPC)continues to follow Moore\'s law,with many comput......
Development is a sophisticated process maintained by various signal transduction pathways,including the Hedgehog(Hh)path......
目的:分析小剂量多巴酚丁胺早期干预治疗肺炎合并脓毒症的效果。方法:回顾性分析台州市第一人民医院2015年1月至2018年1月收治的肺......
Nanomedicine for acute respiratory distress syndrome:The latest application,targeting strategy,and r
Acute respiratory distress syndrome (ARDS) is characterized by the severe inflammation and destruction of the lung air-b......
Designing nanocarriers to overcome the limitations in conventional drug administration for Parkinson
Neurodegenerative diseases (NDs) have become one of the leading causes of death and disability worldwide, and cause enor......
Rational design and synthesis of upconversion luminescence-based optomagnetic multifunctional nanora
Optomagnetic multifunctional composite based on upconversion luminescence nanomaterial is regarded as a promising strate......
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Poly(2-ethyl-2-oxazoline) conjugate of doxorubicin bound via pH-sensitive hydrazone linker:compariso
Polymer conjugates of doxorubicin (DOX) bound via hydrazone linker represent a very promising tool for cancer chemothera......
Application of nanobiotechnology to deliver therapeutic drugs selectively to diseased sites with imp
A number of drugs only give rise to limited clinical response when causing remarkable toxicities due to wide distributio......
Dopamine plays multiple important roles in the brain and body,which is closely associated with several neurological diso......
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Background: Introduce high throughput drug screening technology research progress.Methods: According to the papers publi......
Intervention effect and dose-dependent response of Tanreqing injection on airway mucus hypersecretio
OBJECTIVE:To assess the effect and dose-response relationships of Tanreqing injection on Lipopolysacchaide(LPS)induced a......
Dynamic Subunit Stoichiometry Confers a Progressive Continuum of Pharmacological Sensitivity by KCNQ
Voltage-gated KCNQ1 potassium channels are expressed abundantly in heart but are also found in multiple other tissues.Di......
Csp3-Ⅰ bond,especially those with β-hydrogen atoms,are a class of challenging substrates for the palladium-catalyzed t......
Clinical investigation of Bufeixiaoji decoction in the treatment of patients with advanced refractor
Objective: To evaluate the curative effect and side-reactions of Bufeixiaoji decoction,a Chinese herbal drug in the trea......
Nanofibers containing various amount of EDTA&sodium cholate(SC) were made from 12%(w/v) poly(L-Lactide-co-caprolactone) ......
We focus a monolithic silica as a new sorbent for sample extraction of drugs in biological materials.The monolithic sili......
Evaluation of newly developed 3 micron HILIC columns for separation of hydrophilic compounds includi
Three micron hydrophilic interaction liquid chromatography (HILIC) columns, TSKgel Amide-80 3μm were developed for use ......
Preparation and Spectroscopic of Vanadyl(Ⅱ) Vitamin D3 Amino Acid Mixed Complexes as Insulin Mimetic
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目的:确定混合右美托咪定时0.5%罗哌卡因用于超声引导股神经阻滞按股神经横截面积用药的EDn 50 。n 方法:选择行髌骨骨折......
目的 关于慢性乙型肝炎患者接受核苷类似物实施抗病毒治疗发生耐药停药之后的临床分析。方法 对2018年3月至2021年3月到我院接受治......
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Many drug candidates identified from natural products are poorly water-soluble.The surfactants used to disperse the hydr......
药物治疗是儿童哮喘长期治疗的主要方式，在评价药物治疗有效性的同时，需要关注药物的安全性，哮喘治疗药物不良反应的识别及预防应得到......
Compound Kushen Injection(CKI),as a clinical traditional Chinese medicine preparation,has prominent antitumor effect but......
The incidence and mortality of hepatocellular carcinoma have continued to increase over the last few years,and the medic......
Practice and Effect Evaluation of Drug Reorganization in Patients with Chronic Obstructive Pulmonary
Objective:To explore the feasibility of drug reorganization in clinical practice through the drug reorganization service......
Antibacterial resistance patterns of Acinetobacter baumannii complex:The results of Isfahan Antimicr
Objective: To determine the antibiotic resistance patterns of the Acinetobacter(A.) baumannii complex isolates that caus......
Modeling and simulation for individualized therapy of amisulpride in Chinese patients with schizophr
OBJECTIVE To explain the high inter-individual variability and the frequency of exceeding the therapeutic reference rang......
Targeting the resolution pathway of inflammation using Ac2–26 peptide-loaded PEGylated lipid nanopar
Rheumatoid arthritis(RA)is a common autoimmune disease characterized by joint inflammation and immune dysfunction.Althou......
The present review sets out to discuss recent developments of the effects and mechanisms of carrier properties on their ......
Acute kidney injury(AKI)is a serious kidney disease without specific medications currently except for expensive dialysis......
Among all contaminants of emerging interest,drugs are the ones that give rise to the greatest concern.Any of the multipl......
Proteomics is the complete evaluation of the function and structure of proteins to understand an organism’s nature.Mass......
Data Mining Method for Exploring the Composition Law and Therapeutic Mechanism of Chinese medicine o
Background:Based on the theory of“cancer toxin”in traditional Chinese medicine(TCM),combined with data mining method,t......
<b>Background:</b> The antibiotic susceptibility of bacterial interaction with soot, a by-product of incomplete combusti......
For time being， the most controversial but widely-used animal research， also known as animal experimentation or animal tes......
Drug use during pregnancy is not common.Drug-induced liver injury(DILI)is a potential complication that is rare but can ......
BACKGROUND Vancomycin is often used as an anti-infective drug in patients receiving antitumor chemotherapy.There are con......
Although a key tenant of the Sustainable Development Goals is to achieve universal health coverage,the global drug gap p......
Isolation and Identification of Bacterial Pathogens of Proteus vulgaris and Chryseobacterium meningo
Isolation and Identification of Bacterial Pathogens of Proteus vulgaris and Chryseobacterium meningosepticum from Peodis......
BACKGROUND There are no effective antiviral therapies for coronavirus disease 2019(COVID-19)at present.Although most pat......
BACKGROUND Acute coronary syndrome(ACS)encompasses a spectrum of cardiovascular emergencies arising from the obstruction......
The coronavirus disease 2019(COVID-19)pandemic imposed arestructuring of global health systems by rethinking spaces used......
BACKGROUND In this study,recent trends in the distribution and drug resistance of pathogenic bacteria isolated from pati......
